Staśczak A, Stankiewicz A, Topa J, Piesik Z, Żaczek A, Student S, Stokowy T, Markiewicz A.
Mitochondrial transcript abundance in breast cancer circulating tumour cells may reflect both blood-derived transcripts and biological heterogeneity. Clinical and Experimental Metastasis
Accepted 7 September 2026
Publications
Topa J, Richert J, Stokowy T, Staśczak A, Szajewski M, Ciesielski M, Grešner PM, Tomasik B, Arcimowicz Ł, Stankiewicz A, Suchodolska G, Senkus E, Kruszewski W, Żaczek AJ, Markiewicz A.
Characterizing epithelial-mesenchymal-transition-linked heterogeneity in breast cancer circulating tumor cells at a single-cell level
Molecular Oncology 19(12), 2025
Guetter S, König C, Koerkel-Qu H, Markiewicz A, Scheitler S, Katzer M, Berneburg M, Renner P, Cucuruz B, Guttenberger L, Naimer V, Weidele K, Treitschke S, Werno C, Jaser H, Bargmann T, Braun A, Weber F, Evert K, Rochwarger A, Schürch CM, Limm K, Oefner PJ, Rachel R, Baumann F, Warfsmann J, Schmidleithner L, Guetter K, Mohammadi P, Ulmer A, Haferkamp S, Klein CA, Werner-Klein M.
MCSP+ metastasis founder cells activate immunosuppression early in human melanoma metastatic colonization Nature Cancer 6, 2025
Markiewicz A.
A mass cytometry-based lens on DNA damage repair in circulating tumor cells from breast cancer patients
International Journal of Cancer, August 2025
Muchlinska A, Wenta R, Scinska W, Markiewicz A, Suchodolska G, Senkus E, Zaczek AJ, Bednarz-Knoll N.
Improved characterization of circulating tumor cells and cancer-associated fibroblasts in breast cancer patients using imaging flow cytometry
Cancers 15(16), 2023
Xiao X, Miao X, Duan S, Liu S, Cao Q, Wu R, Tao C, Zhao J, Qu Q, Markiewicz A, Peng R, Chen Y, Żaczek A, Liu J.
Single-Cell Enzymatic Screening for Epithelial Mesenchymal Transition with an Ultrasensitive Superwetting Droplet-Array Microchip
Small Methods, 22 April 2023
Markiewicz A, Topa J, Popeda M, Szade J, Skokowski J, Welnicka-Jaskiewicz M, Zaczek AJ.
Activation of epithelial-mesenchymal transition process during breast cancer progression – the impact of molecular subtype and stromal composition
Acta Biochemica Polonica 68(3), 2021
Topa J, Grešner P, Żaczek AJ, Markiewicz A.
Breast cancer circulating tumor cells with mesenchymal features—an unreachable target?
Cellular and Molecular Life Sciences 79(2), 2021
Popeda M, Markiewicz A, Stokowy T, Szade J, Niemira M, Kretowski A, Bednarz-Knoll N, Zaczek AJ.
Reduced expression of innate immunity-related genes in lymph node metastases of luminal breast cancer patients
Scientific Reports 11, 5097, 2021
Popeda M, Stokowy T, Bednarz-Knoll N, Jurek A, Niemira M, Bielska A, Kretowski A, Kalinowski L, Szade J, Markiewicz A, Zaczek AJ.
NF-kappa B Signaling-Related Signatures Are Connected with the Mesenchymal Phenotype of Circulating Tumor Cells in Non-Metastatic Breast Cancer
Cancers 11(12), 1961, 2019
Nagel A, Szade J, Iliszko M, Elzanowska J, Welnicka-Jaskiewicz M, Skokowski J, Stasilojc G, Bigda J, Sadej R, Zaczek A, Markiewicz A.
Clinical and biological significance of ESR1 gene alteration and estrogen receptors isoforms expression in breast cancer patients
International Journal of Molecular Sciences 20(8), 1881, 2019
Markiewicz A, Topa J, Nagel A, Skokowski J, Seroczynska B, Stokowy T, Welnicka-Jaskiewicz M, Zaczek AJ.
Spectrum of epithelial-mesenchymal transition phenotypes in circulating tumour cells from early breast cancer patients Cancers 11(1), 59, 2019
Weidele K, Stojanović N, Feliciello G, Markiewicz A, Scheitler S, Alberter B, Renner P, Haferkamp S, Klein CA, Polzer B.
Microfluidic enrichment, isolation and characterization of disseminated melanoma cells from lymph node samples
International Journal of Cancer 145, 232–241, 2019
Braun M, Markiewicz A, Kordek R, Sądej R, Romańska H. Profiling of Invasive Breast Carcinoma Circulating Tumour Cells—Are We Ready for the ‘Liquid’ Revolution?
Cancers 11(2), 143, 2019
Markiewicz A, Nagel A, Szade J, Majewska H, Skokowski J, Seroczyńska B, Stokowy T, Wełnicka-Jaśkiewicz M, Zaczek AJ.
Aggressive phenotype of cells disseminated via hematogenous and lymphatic route in breast cancer patients
Translational Oncology 11(3), 2018
Werner-Klein M, Scheitler S, Hoffmann M, Hodak I, Dietz K, Lehnert P, Naimer V, Polzer B, Treitschke S, Werno C, Markiewicz A, Weidele K, Czyz Z, Hohenleutner U, Hafner C, Haferkamp S, Berneburg M, Rümmele P, Ulmer A, Klein CA.
Genetic alterations driving metastatic colony formation are acquired outside of the primary tumour in melanoma
Nature Communications 9, 595, 2018
Markiewicz A, Żaczek A.
The Landscape of Circulating Tumor Cell Research in the Context of Epithelial-Mesenchymal Transition
Pathobiology 84(5), 264–283, 2017
Markiewicz A, Wełnicka-Jaśkiewicz M, Seroczyńska B, Skokowski J, Majewska H, Szade J, Zaczek AJ.
Epithelial-mesenchymal transition markers in lymph node metastases and primary breast tumors - relation to dissemination and proliferation
American Journal of Translational Research 6(6), 793-808, 2014
Markiewicz A, Książkiewicz M, Wełnicka-Jaśkiewicz M, Seroczyńska B, Skokowski J, Szade J, Zaczek AJ.
Mesenchymal Phenotype of CTC-enriched Blood Fraction and Lymph Node Metastasis Formation Potential
PLoS ONE 9(4), e93901, 2014
Markiewicz A, Wełnicka-Jaśkiewicz M, Skokowski J, Jaśkiewicz J, Szade J, Jassem J, Żaczek AJ.
Prognostic Significance of ESR1 Amplification and ESR1 PvuII, CYP2C19*2, UGT2B15*2 Polymorphisms in Breast Cancer Patients
PLoS ONE 8(8), e72219, 2013
Markiewicz A, Książkiewicz M, Seroczyńska B, Skokowski J, Szade J, Wełnicka-Jaśkiewicz M, Zaczek AJ.
Heterogeneity of mesenchymal markers expression—molecular profiles of cancer cells disseminated by lymphatic and hematogenous routes in breast cancer
Cancers 5(4), 1485-1503, 2013
Markiewicz A, Ahrends T, Wełnicka-Jaśkiewicz M, Seroczyńska B, Skokowski J, Jaśkiewicz J, Szade J, Biernat W, Żaczek A.
Expression of epithelial to mesenchymal transition-related markers in lymph node metastases as a surrogate for primary tumor metastatic potential in breast cancer
Journal of Translational Medicine 10, 226, 2012
Żaczek A, Markiewicz A, Seroczyńska B, Skokowski J, Jaśkiewicz J, Pieńkowski T, Olszewski W, Rhone P, Wełnicka-Jaśkiewicz M, Jassem J.
Prognostic Significance of TOP2A Gene Dosage in HER2-negative Breast Cancer
The Oncologist 17, 1246–1255, 2012
Żaczek A, Markiewicz A, Supernat A, Bednarz-Knoll N, Brandt B, Seroczyńska B, Skokowski J, Szade J, Czapiewski P, Biernat W, Wełnicka-Jaśkiewicz M, Jassem J.
Prognostic Value of TOP2A Gene Amplification and Chromosome 17 Polysomy in Early Breast Cancer
Pathology & Oncology Research 18, 885–894, 2012
Supernat A, Markiewicz A, Wełnicka-Jaśkiewicz M, Seroczyńska B, Skokowski J, Sejda A, Szade J, Czapiewski P, Biernat W, Żaczek A.
CD73 expression as a potential marker of good prognosis in breast carcinoma
Applied Immunohistochemistry & Molecular Morphology 20, 103–107, 2012
Książkiewicz M*, Markiewicz A*, Żaczek A.
Epithelial-Mesenchymal Transition: A Hallmark in Metastasis Formation Linking Circulating Tumor Cells and Cancer Stem Cells
Pathobiology 79(4), 195-208, 2012
Żaczek A, Markiewicz A, Jaśkiewicz J, Pieńkowski T, Rhone P, Jassem J, Wełnicka-Jaśkiewicz M.
Clinical evaluation of developed PCR-based method with hydrolysis probes for TOP2A copy number evaluation in breast cancer samples
Clinical Biochemistry 43, 891-898, 2010